Naszai, M. Insect Biochemistry and Molecular Biology , 67, pp. Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches. The intestinal epithelium has a remarkable regenerative capacity, which has made it a prime paradigm for the study of stem cell-driven tissue self-renewal.
DOI: Studies of the adult Drosophila midgut have provided a number of insights on cell type diversity, stem cell regeneration, tissue homeostasis and cell fate decision. Advances in single-cell RNA sequencing scRNA-seq provide opportunities to identify new cell types and molecular features
Flygut : an atlas of the Drosophila adult midgut. An interactive Database that aims to provide a comprehensive atlas of the Drosophila melanogaster adult midgut. You will find an exhaustive description of the different regions of the adult midgut, including the coordinates of each region, their anatomical and histological characteristics, as well as gut- and region-specific gene expression data.